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Copa Libertadores 2025 - Bet on South American Football

Stake - July 31, 2025
News Content

Copa Libertadores 2025 Predictions - South America Football Betting Picks & Odds

The CONMEBOL Libertadores is the biggest and most important South American soccer tournament, featuring the best teams from across the continent. You can bet on all the matches here at Stake Sportsbook, but make sure you check out our football predictions on this page before making your picks.

What is Copa Libertadores?

The Copa Libertadores is an annual soccer tournament featuring the top club teams from across South America. It’s the highest level of competition in South American club football and is organised by CONMEBOL. It’s equivalent to the UEFA Champions League, while the Copa Sudamericana is equivalent to the Europa League, although the format is different for each.

47 teams from 10 associations take part in the tournament, with winners able to qualify for the FIFA Club World Cup, the FIFA Intercontinental Cup and the Recopa Sudamericana.

Copa Libertadores History & Past Winners

The first proper continental tournament in South America was the South American Championship of Champions, which was held in 1948 and won by Vasco de Gama of the Brazilian Serie A. It helped inspire the first European Cup, which would later become the Champions League. However, it had just one edition, and it wasn’t until later that a regular continental competition would be created in South America.

In 1958, the Copa de Campeones de América was introduced as a South American equivalent to the European Cup. The very first edition of the tournament was held in 1960 and featured 7 teams. Since then, it has expanded significantly and in 1965, it was named Copa Libertadores after the heroes of South American liberation.

There have been 27 winners of the Copa Libertadores:

  • Independiente: 7 titles

  • Boca Juniors: 6 titles

  • Peñarol: 5 titles

  • River Plate: 4 titles

  • Estudiantes: 4 titles

  • Olimpia: 3 titles

  • Nacional: 3 titles

  • São Paulo: 3 titles

  • Palmeiras: 3 titles

  • Santos: 3 titles

  • Grêmio: 3 titles

  • Flamengo: 3 titles

  • Cruzeiro: 2 titles

  • Internacional: 2 titles

  • Atlético Nacional: 2 titles

  • Colo-Colo: 2 titles

  • Atlético Mineiro: 1 title

  • Fluminese: 1 title

  • Racing Club: 1 title

  • Argentinos Juniors: 1 title

  • Vélez Sársfield: 1 title

  • Vasco da Gama: 1 title

  • Once Caldas: 1 title

  • LDU Quito: 1 title

  • Corinthians: 1 title

  • San Lorenzo: 1 title

  • Botofogo: 1 title

2025 Copa Libertadores Schedule & Format

The 2025 Copa Libertadores features 8 stages, the first of which began in January. The top 4 teams from the first 3 stages qualify for the group stage, along with 28 teams that automatically qualified. During the group stage, there are 8 groups of 4 teams, and every team plays each opponent twice. The group winners and runners-up then enter the knockout rounds, which lead to the final in November 2025.

Here are the full dates for the 2025 Copa Libertadores:

  • First stage: 4-6 and 11-13 February

  • Second stage: 18-20 and 25-27 February

  • Third stage: 4-6 and 11-13 March

  • Group stage: 1 April - 29 May

  • Round of 16: 12-14 and 19-21 August

  • Quarter-finals: 16-18 and 23-25 September

  • Semi-finals: 21-23 October and 28-30 October

  • Final: 29 November in Lima, Peru

Stats, News & Results so Far

The round of 16 is made from the group stage winners and runners-up. Teams are seeded based on their performance during the group stage, and this seeding then determines their initial bracket draw. Here are the matchups for the round of 16:

  • Atlético Nacional vs São Paulo

  • Botafogo vs LDU Quito

  • Universitario vs Palmeiras

  • Libertad vs River Plate

  • Fortaleza vs Vélez Sarsfield

  • Peñarol vs Racing

  • Flamengo vs Internacional

  • Cerro Porteño vs Estudiantes

Copa Libertadores Picks & Predictions for 2025

The Copa Libertadores is notoriously hard to predict, as many evenly matched teams all have a chance of lifting the trophy. In recent years, Brazilian teams have dominated the tournament, winning the last 6 Copa Libertadores.

Who Will Win the Copa Libertadores?

  1. Flamengo - Flamengo are the current favourites to win the 2025 Copa Libertadores. They were runners-up in Group C, coming behind LDU Quito on goal difference. However, they recently had some great performances at the Club World Cup, beating the eventual champions, Chelsea, in the group stage.

  2. Palmeiras - Palmeiras were the number 1 seeded team after the group stage, having finished with 6 wins and 17 goals scored while conceding just 4. They did have a relatively easy group, but their excellent performances have them as the 2nd favourites to win currently.

  3. River Plate - Argentine Primera Division team River Plate have won the Cop Libertadores 4 times in their history, and they’re currently the 3rd favourites this year. However, their last win was in 2018, and they’ll likely have to get past Palmeiras in the quarter-finals if they progress past the round of 16.

Types of Soccer Bets & How to Bet on Copa Libertadores

Betting at Stake is straightforward, but you can read our guide to soccer betting and our ultimate sports betting guide to learn how to get started. We’ve also outlined the most important steps below:

  1. Log in to your Stake.com account and check your current balance in the wallet.

  2. If you need to, select the deposit option and choose any of the supported local currencies and payment methods.

  3. You can also bet with crypto at Stake, with a wide range of popular cryptocurrencies available, including BTC, ETH, USDT, EOS, DOGE, LTC, TRX, and SOL.

  4. Deposit crypto with Mesh, or use Swapped.com or MoonPay to easily add crypto before storing your funds in the Stake vault for safety.

  5. Search for any of the teams in the competition or for the Copa Libertadores, or look for Soccer > International Clubs > CONMEBOL Libertadores.

  6. Look through all the live and upcoming matches to bet on.

  7. Choose any match to see all the available betting markets and select one to add to your bet slip.

  8. Enter your stake and check the potential payout before confirming your bet.

There are many different soccer betting markets available on Copa Libertadores games at Stake, including:

  • 1x2

  • Draw no bet

  • Asian total

  • Asian handicap betting

  • Double chance

  • 1st goal

  • Correct score

  • Both teams to score

  • Halftime/fulltime

  • Same-game parlay

  • Outright

Live Stream Major Football/Soccer Matches Online

You can find a variety of live betting options on soccer and live stats at Stake. To see the live odds, simply open the match while it’s happening. Free live streams are also available on selected matches from soccer leagues around the world. Just select the live icon to watch the game and enjoy the action. Find out the difference between pre-match and live betting in our guide.

Copa Libertadores Betting Odds, Payouts & Promotions

Before betting on the Copa Libertadores, make sure you understand how to read betting odds and what the vig is. This will help you get the best value from betting platforms and hopefully land better payouts too. You can also enjoy sports betting promotions at Stake to get more out of your betting experience.

Soccer & Football Betting Tips, Predictions & Strategies

  1. Consider fatigue and altitude - South American soccer can be very hectic, with busy fixture schedules meaning some teams play multiple games a week. What’s more, travel times can be rough, especially for the Copa Libertadores. Many games are also played at altitude, especially in places such as La Paz, Quito and Bogota, which can have a major impact on player performances.

  2. Research the stats - Make sure you read match previews and follow all the latest stats, including recent team and player form. Consider how well a team is playing in their domestic league, as well as previous matches in the Copa Libertadores. Last season, 2.39 goals were scored per game, while the home team usually had a major advantage, winning 54% of games.

  3. Make the most of all the betting markets - There are more than 70 different betting markets on each Copa Libertadores match, and many different live betting options too. Take advantage of all the available markets aside from the match winner bet to find the best value and use the data and stats to back up your sports predictions.

Stake VIP Club & Responsible Betting

Joining Stake also means becoming a member of our VIP Club, which lets you level up your account to unlock exclusive rewards. As you place bets, you can increase your level to receive regular rakeback, reload bonuses and even your own VIP host. Find out how it all works on the VIP FAQ page.

To make sure that you stay in control whenever you're betting at Stake, be sure to follow our Stake Smart guidelines and bet responsibly.

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